LATENT EFFECTS OF GESTATIONAL EXPOSURE TO HEPTACHLOR
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چکیده
منابع مشابه
Dopamine transporter binding in the rat striatum is increased by gestational, perinatal, and adolescent exposure to heptachlor.
Heptachlor is a persistent cyclodiene pesticide that affects GABAergic function. Recent reports indicate that heptachlor exposure also alters dopamine transporter (DAT) expression and function in adult mice. The aim of this study was to determine whether gestational, perinatal, and/or adolescent heptachlor exposure in rats altered dopamine-receptor and DAT binding. Adolescent exposure to dieldr...
متن کاملHeptachlor and Heptachlor Epoxide
9. REFERENCES ACGIH. 1986. Documentation of the threshold limit valves and biological exposure indices. 5th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, 296. ACGIH. 2004. Threshold limit values for chemical substances and physical agents and biological exposure indices. Cincinnati, OH: American Conference of Governmental Industrial Hygienists. Adeshina F, Todd ...
متن کاملThe effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats.
This study was performed to determine if developmental exposure of rats to heptachlor (H) during the last half of gestation through puberty adversely affects adult functioning of the immune and reproductive systems. Time-bred pregnant female Sprague-Dawley rats were dosed by gavage with H (0, 30, 300, or 3000 microg/kg/day) from gestation day (GD) 12 to postnatal day (PND) 7, followed by direct...
متن کاملNeurotoxicological outcomes of perinatal heptachlor exposure in the rat.
The developing nervous system has been identified as a potential target of pesticide exposure. Heptachlor is a cyclodiene pesticide that was widely used for many years, and for which inadvertent exposure to children and fetuses took place in the early 1980s; yet little is known regarding the developmental neurotoxicity of it and other cyclodienes. The aim of this study was to determine whether ...
متن کاملExposure to Predator Stress in Gestational Period Potentiates Pilocarpine induced Epileptic Behaviors in offspring of rat
Introduction: Gestational stress can lead to cerebral functional disorders, such as epilepsy, probably due to the disturbance in the cerebral maturation and causing abnormal neuronal correlations. In the present study, effect of gestational Predator Stress on the neonatal epileptic behaviors was investigated in rats. Methods: Female rats (200 ± 20 g) were divided into two groups intact pregn...
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ژورنال
عنوان ژورنال: Epidemiology
سال: 2004
ISSN: 1044-3983
DOI: 10.1097/00001648-200407000-00303